MazicBay Diagnostics
MAZICBAYDiagnostics
FTC Reader Disclosure: When you purchase or register through links on our site, we may earn an affiliate commission at no extra cost to you. Read our Editorial & Advertising Policy.

P0300 on Chrysler 300

Random or Multiple Cylinder Misfire Detected

Factory diagnostic protocol and troubleshooting wire for fault code P0300 specifically for the Chrysler 300 (2020–2025, 3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8)).

Verified OEM Telemetry & Field Repair Tree
Chrysler 3002020–2025
Chrysler 300
Sedan3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8)
Reliability
Sensor Voltage Ref
0.1V – 5.0V Ref
300 SAE Mode $01
ECU Network Bus
500 kbps CAN-FD
ISO 15765-4 Compliant
Drivability Status
Not Recommended
Critical urgency level
Est. Repair Cost
$100 - $600 (DIY: $30 - $120)
Parts & Labor DIY
Check P0300 On Another Chrysler Model:
Diagnose P0300 on Specific 300 Model Year:

1. Symptoms of P0300 on Chrysler 300

When the Engine Control Module (ECM/PCM) on your Chrysler 300 (3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8)) logs fault code P0300, drivers commonly observe:

Flashing Check Engine Light (CEL) on Chrysler 300 (3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8))
Engine shaking, vibrating, or jerking at idle on Chrysler 300 (3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8))
Noticeable loss of engine power when accelerating on Chrysler 300 (3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8))
Strong gasoline smell from exhaust or poor fuel economy on Chrysler 300 (3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8))
Stumbling or stalling at stoplights on Chrysler 300 (3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8))
Chrysler 300 OBD-II Port Location
The 16-pin diagnostic connector is located Under driver side dash near left knee panel. Plug in your scan tool to verify freeze-frame sensor values.

2. Most Likely Causes on Chrysler 300

Historical warranty claims and technical repair bulletins for Chrysler 300 point to the following failure distribution:

55%
Worn or fouled spark plugs and damaged spark plug wires (Chrysler OEM Part)
25%
Failing ignition coils or coil packs (Chrysler OEM Part)
12%
Clogged fuel injectors or low fuel rail pressure (Chrysler OEM Part)
8%
Intake manifold vacuum leak (Chrysler OEM Part)
8%
Low engine compression or faulty Camshaft/Crankshaft sensor (Chrysler OEM Part)
* Source: Synthesized from NHTSA ODI field repair telemetry and verified OEM Technical Service Bulletin (TSB) repair tree frequency percentiles for Chrysler 300.

3. Step-by-Step DIY Repair Guide for Chrysler 300

01
Scan with OBD-II Scanner for Accompanying Codes

Plug a handheld OBD-II scanner into the 16-pin port under the dashboard. Check if specific cylinder codes like P0301 (Cylinder 1) or P0304 (Cylinder 4) accompany P0300. on the Chrysler 300 equipped with 3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8).

Required Tool: OBD-II Code Reader / Scanner
02
Inspect and Replace Spark Plugs

Remove the ignition coils, use a spark plug socket with ratchet to unthread spark plugs. Inspect electrode tips for carbon buildup, oil fouling, or burnt gaps. Replace with OEM iridium plugs gapped to spec. on the Chrysler 300 equipped with 3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8).

Required Tool: 5/8 Spark Plug Socket, Ratchet Extension, Gap Gauge
03
Test Ignition Coils

Perform an ignition swap test: Swap coil from a suspected misfiring cylinder to an adjacent cylinder. Clear codes and re-scan. If the misfire moves, replace the faulty coil. on the Chrysler 300 equipped with 3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8).

Required Tool: 10mm Socket, Multimeter
04
Check for Vacuum Leaks

Inspect PCV hoses, intake boot, and vacuum lines for cracking or hissing sounds while engine idles. Smoke test the intake if necessary. on the Chrysler 300 equipped with 3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8).

Required Tool: Carb cleaner spray or Smoke machine
05
Verify Fuel Delivery and Clear DTC Codes

Add a bottle of premium fuel injector cleaner (e.g. Chevron Techron). Clear the OBD-II codes with your scanner and take the car on a 15-minute drive cycle to confirm readiness monitors reset. on the Chrysler 300 equipped with 3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8).

Required Tool: OBD-II Scanner
Recommended Parts & Testing Tools

Equipment for Diagnosing Chrysler 300 (P0300)

Prime Fast Delivery & Verified Fitment
OEM Ignition Component

Direct-Fit Laser Iridium Spark Plugs (Set of 4/6)

4.8 / 5.0 (Top Rated)

Pre-gapped iridium spark plugs engineered to restore smooth combustion on Chrysler 300.

$36 – $68 Prime
Check Price on Amazon
Ignition Service Tool

Magnetic Swivel Spark Plug Socket Set

4.8 / 5.0 (Amazon Choice)

360-degree magnetic swivel socket prevents ceramic plug cracks inside deep engine spark wells.

$16.99 Prime
View on Amazon
Top Mobile OBD-II Scanner

BlueDriver Bluetooth Pro OBDII Scan Tool

4.7 / 5.0 (50,000+ Reviews)

Reads and clears enhanced codes (ABS, Airbag, Transmission, Engine) & live freeze-frame telemetry on phone.

Compare OEM & Aftermarket Replacement Sensors for Chrysler 300Verified direct-fit pricing from Denso, Bosch, Motorcraft, and ACDelco on Amazon.
Find Parts on Amazon
* As an Amazon Associate, MazicBay earns from qualifying purchases. Prices & availability subject to change.

Other Common Fault Codes on Chrysler 300

Frequently diagnosed powertrain, emissions, and sensor trouble codes logged on the Chrysler 300:

4. Chrysler 300 P0300 FAQs

What causes code P0300 to trigger on a Chrysler 300?

On the Chrysler 300 (3.6L Pentastar V6 (292HP) / 5.7L / 6.4L 392 HEMI V8 (485HP SRT8)), P0300 is most frequently caused by Worn or fouled spark plugs and damaged spark plug wires or Failing ignition coils or coil packs.

Where is the OBD-II port located on my Chrysler 300?

On the Chrysler 300, the 16-pin DLC diagnostic connector is located Under driver side dash near left knee panel. Plug in any standard OBD-II scanner with the ignition in the ON position to read freeze-frame parameters.

Can I safely drive my Chrysler 300 with code P0300?

No. Driving with a flashing check engine light causes irreversible catalytic converter damage. Given that P0300 carries a Critical severity rating, we advise avoiding heavy towing or aggressive throttle inputs until sensor readings are verified.