P0354 on Lexus IS
Factory diagnostic protocol and troubleshooting wire for fault code P0354 specifically for the Lexus IS (2020–2026, 2.0L Turbo / 3.5L V6 (IS 350 311HP) / 5.0L Naturally Aspirated V8 (IS 500 472HP)).
1. Symptoms of P0354 on Lexus IS
When the Engine Control Module (ECM/PCM) on your Lexus IS (2.0L Turbo / 3.5L V6 (IS 350 311HP) / 5.0L Naturally Aspirated V8 (IS 500 472HP)) logs fault code P0354, drivers commonly observe:
2. Most Likely Causes on Lexus IS
Historical warranty claims and technical repair bulletins for Lexus IS point to the following failure distribution:
3. Step-by-Step DIY Repair Guide for Lexus IS
Swap Coil 4 to Cylinder 1. on the Lexus IS equipped with 2.0L Turbo / 3.5L V6 (IS 350 311HP) / 5.0L Naturally Aspirated V8 (IS 500 472HP).
Install new OEM coil pack. on the Lexus IS equipped with 2.0L Turbo / 3.5L V6 (IS 350 311HP) / 5.0L Naturally Aspirated V8 (IS 500 472HP).
Clear memory and road test. on the Lexus IS equipped with 2.0L Turbo / 3.5L V6 (IS 350 311HP) / 5.0L Naturally Aspirated V8 (IS 500 472HP).
Equipment for Diagnosing Lexus IS (P0354)
Direct-Fit Laser Iridium Spark Plugs (Set of 4/6)
Pre-gapped iridium spark plugs engineered to restore smooth combustion on Lexus IS.
Magnetic Swivel Spark Plug Socket Set
360-degree magnetic swivel socket prevents ceramic plug cracks inside deep engine spark wells.
BlueDriver Bluetooth Pro OBDII Scan Tool
Reads and clears enhanced codes (ABS, Airbag, Transmission, Engine) & live freeze-frame telemetry on phone.
Other Common Fault Codes on Lexus IS
Frequently diagnosed powertrain, emissions, and sensor trouble codes logged on the Lexus IS:
4. Lexus IS P0354 FAQs
What causes code P0354 to trigger on a Lexus IS?
On the Lexus IS (2.0L Turbo / 3.5L V6 (IS 350 311HP) / 5.0L Naturally Aspirated V8 (IS 500 472HP)), P0354 is most frequently caused by Dead Cylinder 4 ignition coil or Wiring damage.
Where is the OBD-II port located on my Lexus IS?
On the Lexus IS, the 16-pin DLC diagnostic connector is located Driver A-pillar base kick panel. Plug in any standard OBD-II scanner with the ignition in the ON position to read freeze-frame parameters.
Can I safely drive my Lexus IS with code P0354?
No. Cylinder 4 ignition coil has failed. Given that P0354 carries a Critical severity rating, we advise avoiding heavy towing or aggressive throttle inputs until sensor readings are verified.

